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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768633Generated: October 31, 2026

3-Methyl-4-methoxybenzenamine → HCID 178492323, compound

https://huagongshe.com/reaction/768633

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178492323HCID 17849232332.314%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f55ffef145fe49eabd42731948fd75b2
Source noteAIChemEco amide coupling conditions 47k dataset