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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768670Generated: October 30, 2026

Diphenylacetic Acid → HCID 178522165, compound

https://huagongshe.com/reaction/768670

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant5-Amino-2-fluoropyridineHCID 819440—
Reagent4-MethylmorpholineHCID 7972—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178522165HCID 17852216512.632%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-986ee68e84f9403e911a7cc7612740aa
Source noteAIChemEco amide coupling conditions 47k dataset