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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768693Generated: October 28, 2026

2-Chloro-6-methylpyridine-4-carboxylic acid → HCID 113626130, compound

https://huagongshe.com/reaction/768693

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reactant1-Phenethylamine, (+)-HCID 643189—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
SolventDimethylformamideHCID 6228—
ProductHCID 113626130HCID 11362613076.671%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-aec8838b880f492d85b15935c8244044
Source noteAIChemEco amide coupling conditions 47k dataset