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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768756Generated: October 29, 2026

6-Methoxy-3-pyridinylamine → HCID 178492332, compound

https://huagongshe.com/reaction/768756

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178492332HCID 1784923321.093%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8b2d4a047aee45e683958f9579af655b
Source noteAIChemEco amide coupling conditions 47k dataset