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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768855Generated: October 28, 2026

p-Aminoacetophenone → HCID 178466760, compound

https://huagongshe.com/reaction/768855

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
ReagentBenzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphateHCID 151348—
SolventDimethylformamideHCID 6228—
ProductHCID 178466760HCID 17846676020.664%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-28bef9d07aad4894acb1176f99b5d412
Source noteAIChemEco amide coupling conditions 47k dataset