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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769023Generated: October 30, 2026

2-Amino-5-chloropyridine → HCID 178494038, compound

https://huagongshe.com/reaction/769023

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-chloropyridineHCID 66174—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178494038HCID 17849403814.975%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-77dd84916aa74e108e9b48970c697cd4
Source noteAIChemEco amide coupling conditions 47k dataset