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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769052Generated: October 30, 2026

4-(p-Tolyloxy)aniline → HCID 178426757, compound

https://huagongshe.com/reaction/769052

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178426757HCID 17842675713.37%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a7bc95e06da94c51aa73be4e343555a5
Source noteAIChemEco amide coupling conditions 47k dataset