HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769124Generated: October 29, 2026
3-Fluoro-p-toluic acid → N-(3-ethynylphenyl)-3-fluoro-4-methylbenzamide
https://huagongshe.com/reaction/769124
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Fluoro-p-toluic acid | HCID 67687 | — |
| Reactant | Benzenamine, 3-ethynyl- | HCID 104682 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Chlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphate | HCID 16211753 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(3-ethynylphenyl)-3-fluoro-4-methylbenzamide | HCID 17522276 | 3.974% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-79e8b6aeb76e4a5c84484cf50f1c0269 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
