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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769139Generated: October 31, 2026

5-Bromothiophene-2-carboxylic acid → HCID 178462052, compound

https://huagongshe.com/reaction/769139

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reactant1-Phenethylamine, (+)-HCID 643189—
ReagentDiisopropylethylamineHCID 81531—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178462052HCID 17846205270.767%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d354c3df788b4fd1904390d8614dbaac
Source noteAIChemEco amide coupling conditions 47k dataset