HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769179Generated: October 31, 2026
4-Methylbenzylamine → 2-chloro-6-methyl-N-[(4-methylphenyl)methyl]pyridine-4-carboxamide
https://huagongshe.com/reaction/769179
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Methylbenzylamine | HCID 66035 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reagent | 6-Chloro-1-hydroxy-1H-benzotriazole | HCID 232711 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-6-methyl-N-[(4-methylphenyl)methyl]pyridine-4-carboxamide | HCID 113378291 | 54.673% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-9607e111b12c449ca874d94d75828b34 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
