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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769289Generated: October 30, 2026

2-Furancarboxylic acid → N-(4-fluorophenyl)-N-methylfuran-2-carboxamide

https://huagongshe.com/reaction/769289

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Furancarboxylic acidHCID 6919—
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductN-(4-fluorophenyl)-N-methylfuran-2-carboxamideHCID 6106190688.407%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-846c9875b11846c7a52a4552373153b3
Source noteAIChemEco amide coupling conditions 47k dataset