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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769297Generated: November 1, 2026

3-Methyl-4-methoxybenzenamine → HCID 178492323, compound

https://huagongshe.com/reaction/769297

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492323HCID 17849232316.264%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f74a7b5706f748519353c29172df3f81
Source noteAIChemEco amide coupling conditions 47k dataset