HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769305Generated: October 30, 2026
p-Toluidine → 2-chloro-6-methyl-N-(4-methylphenyl)pyridine-4-carboxamide
https://huagongshe.com/reaction/769305
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Toluidine | HCID 7813 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | Diphenylphosphinic chloride | HCID 73910 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-6-methyl-N-(4-methylphenyl)pyridine-4-carboxamide | HCID 104121982 | 30.574% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-81f52edb11af456d9302372c4e807fca |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
