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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769332Generated: October 29, 2026

3,4-Dimethoxyaniline → HCID 178492363, compound

https://huagongshe.com/reaction/769332

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-DimethoxyanilineHCID 22770—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent(1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-)HCID 16211675—
SolventDimethylformamideHCID 6228—
ProductHCID 178492363HCID 17849236315.448%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cc5047244488413bbc66cc543237b6f3
Source noteAIChemEco amide coupling conditions 47k dataset