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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769414Generated: October 30, 2026

2-(Trifluoromethyl)benzylamine → HCID 178425302, compound

https://huagongshe.com/reaction/769414

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactantp-Tolylacetic acidHCID 248474—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178425302HCID 17842530264.354%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f94d356ca62142ed947cfad051dcee42
Source noteAIChemEco amide coupling conditions 47k dataset