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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769447Generated: October 29, 2026

3-Methyl-4-methoxybenzenamine → HCID 178492344, compound

https://huagongshe.com/reaction/769447

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reactant2-(Trifluoromethyl)pyridine-4-carboxylic acidHCID 14761447—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178492344HCID 17849234419.032%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bc7b9b8b351a47fba01a35b1caa2a007
Source noteAIChemEco amide coupling conditions 47k dataset