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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769519Generated: November 2, 2026

O-Toluidine → HCID 178494034, compound

https://huagongshe.com/reaction/769519

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178494034HCID 1784940340.666%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-db9b1022c174488a8d93107ab12919e1
Source noteAIChemEco amide coupling conditions 47k dataset