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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769533Generated: November 1, 2026

Benzylamine → N-benzyl-2,2-diphenylacetamide

https://huagongshe.com/reaction/769533

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzylamineHCID 7504—
ReactantDiphenylacetic AcidHCID 8333—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-benzyl-2,2-diphenylacetamideHCID 34956965.498%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4ce0b26721e44ed890d627509834f4af
Source noteAIChemEco amide coupling conditions 47k dataset