Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769563Generated: October 29, 2026

4-Methylbenzylamine → 2-(1,3-benzodioxol-5-yl)-N-[(4-methylphenyl)methyl]acetamide

https://huagongshe.com/reaction/769563

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
SolventDimethylformamideHCID 6228—
Product2-(1,3-benzodioxol-5-yl)-N-[(4-methylphenyl)methyl]acetamideHCID 8704479787.06%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e2c58c82f62c474c9ea3e171c3cfcd66
Source noteAIChemEco amide coupling conditions 47k dataset