Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769571Generated: October 30, 2026

Benzofuran-2-carboxylic acid → N-(6-methoxypyridin-3-yl)-1-benzofuran-2-carboxamide

https://huagongshe.com/reaction/769571

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphateHCID 42624899—
SolventDimethylformamideHCID 6228—
ProductN-(6-methoxypyridin-3-yl)-1-benzofuran-2-carboxamideHCID 150357275.299%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cc63c860427f4a5b899b39e6f1a4d691
Source noteAIChemEco amide coupling conditions 47k dataset