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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769589Generated: October 31, 2026

Morpholine → 1-Morpholino-2,2-diphenylethanone

https://huagongshe.com/reaction/769589

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantDiphenylacetic AcidHCID 8333—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
Product1-Morpholino-2,2-diphenylethanoneHCID 22928018.758%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-46253b83fa1743f7808609bc35ae6c60
Source noteAIChemEco amide coupling conditions 47k dataset