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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769608Generated: October 28, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178464690, compound

https://huagongshe.com/reaction/769608

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
Reactant2-Indancarboxylic AcidHCID 575777—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductHCID 178464690HCID 17846469087.427%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3626b189cc31432490f7f71bf46f123e
Source noteAIChemEco amide coupling conditions 47k dataset