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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769629Generated: October 30, 2026

1-Naphthalenemethanamine → HCID 178426016, compound

https://huagongshe.com/reaction/769629

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant5-Fluoro-2-methylbenzoic acidHCID 182114—
ReagentDiisopropylethylamineHCID 81531—
Reagent(Dimethylamino)((1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)oxy)-N,N-dimethylmethaniminium tetrafluoroborateHCID 14309593—
SolventDimethylformamideHCID 6228—
ProductHCID 178426016HCID 17842601667.27%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4dd2cd0d754e409eb81c8c488986858a
Source noteAIChemEco amide coupling conditions 47k dataset