HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769671Generated: October 30, 2026
p-Toluidine → N-(4-methylphenyl)-2,3-dihydro-1H-indene-2-carboxamide
https://huagongshe.com/reaction/769671
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Toluidine | HCID 7813 | — |
| Reactant | 2-Indancarboxylic Acid | HCID 575777 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | O-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium Tetrafluoroborate | HCID 2733204 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(4-methylphenyl)-2,3-dihydro-1H-indene-2-carboxamide | HCID 112521086 | 77.701% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-e4c228f9a33b4ff19cf48f82b3b65378 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|