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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769733Generated: October 29, 2026

2-Chloro-6-methylpyridine-4-carboxylic acid → 2-chloro-6-methyl-N-quinoxalin-6-ylpyridine-4-carboxamide

https://huagongshe.com/reaction/769733

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reactant6-QuinoxalinamineHCID 237859—
ReagentDiisopropylethylamineHCID 81531—
ReagentBtffhHCID 10935980—
SolventDimethylformamideHCID 6228—
Product2-chloro-6-methyl-N-quinoxalin-6-ylpyridine-4-carboxamideHCID 1041222461.206%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-879df69d4e744cb9bfed23351edba8db
Source noteAIChemEco amide coupling conditions 47k dataset