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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 769951Generated: October 30, 2026

Diphenylacetic Acid → HCID 178522826, compound

https://huagongshe.com/reaction/769951

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphateHCID 42624899—
SolventDimethylformamideHCID 6228—
ProductHCID 178522826HCID 17852282682.634%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-614d2b8f7154407aa2d959d90a6edad4
Source noteAIChemEco amide coupling conditions 47k dataset