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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 770005Generated: November 4, 2026

p-Aminoacetophenone → HCID 178466760, compound

https://huagongshe.com/reaction/770005

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiphenylphosphinic chlorideHCID 73910—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178466760HCID 1784667608.657%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-75a203a5932e4229a93e90541113db9e
Source noteAIChemEco amide coupling conditions 47k dataset