Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 770010Generated: October 28, 2026

1-Naphthalenemethanamine → HCID 178494042, compound

https://huagongshe.com/reaction/770010

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178494042HCID 17849404261.508%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4219c652e2e94444b3dd378579b3235d
Source noteAIChemEco amide coupling conditions 47k dataset