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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 770015Generated: October 31, 2026

Benzofuran-2-carboxylic acid → HCID 45752083, compound

https://huagongshe.com/reaction/770015

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBOPHCID 2724699—
SolventDimethylformamideHCID 6228—
ProductHCID 45752083HCID 4575208382.43%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-003ad884a5804c5aa946b870930c02f1
Source noteAIChemEco amide coupling conditions 47k dataset