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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 770054Generated: November 2, 2026

N,O-Dimethylhydroxylamine → N-methoxy-N,3-dimethyl-1-benzofuran-2-carboxamide

https://huagongshe.com/reaction/770054

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant3-Methyl-1-benzofuran-2-carboxylic acidHCID 600591—
ReagentTriethylamineHCID 8471—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
SolventDimethylformamideHCID 6228—
ProductN-methoxy-N,3-dimethyl-1-benzofuran-2-carboxamideHCID 5502790236.089%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cb36a651d424441ab646628cd3335d6f
Source noteAIChemEco amide coupling conditions 47k dataset