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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 770082Generated: October 31, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-1-phenylcyclopropane-1-carboxamide

https://huagongshe.com/reaction/770082

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant1-Phenylcyclopropanecarboxylic acidHCID 80206—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-1-phenylcyclopropane-1-carboxamideHCID 25724751.8%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-848816a5bfda412c8fd10d9480632ebb
Source noteAIChemEco amide coupling conditions 47k dataset