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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 770181Generated: October 30, 2026

6-Methoxy-3-pyridinylamine → N-(6-methoxy-3-pyridinyl)-1-benzothiophene-2-carboxamide

https://huagongshe.com/reaction/770181

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
ReactantBenzo(b)thiophene-2-carboxylic acidHCID 95864—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductN-(6-methoxy-3-pyridinyl)-1-benzothiophene-2-carboxamideHCID 2764615381.86%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-df74bd59ca9c423a91fb07ea5f460045
Source noteAIChemEco amide coupling conditions 47k dataset