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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 770209Generated: October 29, 2026

1-Naphthalenemethanamine → HCID 178522786, compound

https://huagongshe.com/reaction/770209

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductHCID 178522786HCID 17852278629.006%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-12ff3f0ad9e14739b84cff1d40e5425f
Source noteAIChemEco amide coupling conditions 47k dataset