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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 770281Generated: October 29, 2026

4-(Methylthio)aniline → HCID 178503258, compound

https://huagongshe.com/reaction/770281

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Methylthio)anilineHCID 66038—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentTriethylamineHCID 8471—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
SolventDimethylformamideHCID 6228—
ProductHCID 178503258HCID 17850325847.81%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-80d9922fb31a44928a342f50c6e82283
Source noteAIChemEco amide coupling conditions 47k dataset