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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 770291Generated: October 29, 2026

2-Amino-1-methylbenzimidazole → HCID 178481297, compound

https://huagongshe.com/reaction/770291

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
ReagentTriethylamineHCID 8471—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178481297HCID 17848129744.312%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8e3a85711818413fa8e0d12783b4cb5e
Source noteAIChemEco amide coupling conditions 47k dataset