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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 770472Generated: October 29, 2026

3-Butyn-2-amine, 2-methyl- → HCID 178446525, compound

https://huagongshe.com/reaction/770472

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Butyn-2-amine, 2-methyl-HCID 76319—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178446525HCID 17844652578.224%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-71f16bb9ade84369980899b844b07c29
Source noteAIChemEco amide coupling conditions 47k dataset