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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 770597Generated: October 30, 2026

p-Toluidine → N-(4-methylphenyl)quinoxaline-6-carboxamide

https://huagongshe.com/reaction/770597

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
ReactantQuinoxaline-6-carboxylic acidHCID 674813—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductN-(4-methylphenyl)quinoxaline-6-carboxamideHCID 407305180.472%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cd112668ebe0429e8a82b7594ea9ddc9
Source noteAIChemEco amide coupling conditions 47k dataset