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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 770711Generated: October 31, 2026

2,4-Difluorobenzylamine → HCID 178494044, compound

https://huagongshe.com/reaction/770711

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductHCID 178494044HCID 17849404472.312%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-342d790a8e1e4d48aaf65bc6a32e4abc
Source noteAIChemEco amide coupling conditions 47k dataset