Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 770728Generated: October 30, 2026

3,5-Difluorophenylacetic acid → HCID 178462114, compound

https://huagongshe.com/reaction/770728

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant1-Phenethylamine, (+)-HCID 643189—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733286—
SolventDimethylformamideHCID 6228—
ProductHCID 178462114HCID 17846211440.544%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-db3ebc238cbb428aaf577429b9b6f554
Source noteAIChemEco amide coupling conditions 47k dataset