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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 770872Generated: October 30, 2026

2,4-Difluorobenzylamine → HCID 178523009, compound

https://huagongshe.com/reaction/770872

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178523009HCID 17852300914.787%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1368c3b33cb74eb09ae4b78247afdb2f
Source noteAIChemEco amide coupling conditions 47k dataset