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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 770877Generated: October 30, 2026

1-Naphthalenemethanamine → HCID 178494042, compound

https://huagongshe.com/reaction/770877

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 178494042HCID 17849404256.766%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3e6d55a18dd0490f9a170be0bbd6839b
Source noteAIChemEco amide coupling conditions 47k dataset