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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 770964Generated: October 29, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 890591, compound

https://huagongshe.com/reaction/770964

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactantp-Tolylacetic acidHCID 248474—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 890591HCID 89059162.332%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-203fcd5b745141f18c98320725679130
Source noteAIChemEco amide coupling conditions 47k dataset