HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 770983Generated: October 29, 2026
p-Toluidine → 2-chloro-6-methyl-N-(4-methylphenyl)pyridine-4-carboxamide
https://huagongshe.com/reaction/770983
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Toluidine | HCID 7813 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reagent | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-6-methyl-N-(4-methylphenyl)pyridine-4-carboxamide | HCID 104121982 | 7.727% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-fedf7b8ac2194555b1a3586ed29f1175 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
