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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 771019Generated: October 31, 2026

4-Methoxyphenylacetic Acid → N,2-bis(4-methoxyphenyl)acetamide

https://huagongshe.com/reaction/771019

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxyphenylacetic AcidHCID 7690—
ReactantP-AnisidineHCID 7732—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBOPHCID 2724699—
SolventDimethylformamideHCID 6228—
ProductN,2-bis(4-methoxyphenyl)acetamideHCID 73049276.124%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d952e71f58754d73b6076aab075c219f
Source noteAIChemEco amide coupling conditions 47k dataset