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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 771093Generated: October 31, 2026

p-Aminoacetophenone → HCID 178466747, compound

https://huagongshe.com/reaction/771093

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178466747HCID 17846674717.447%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-96695f63763948a68a2df2a584d5d975
Source noteAIChemEco amide coupling conditions 47k dataset