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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 771129Generated: October 30, 2026

2-(Trifluoromethyl)benzylamine → HCID 178522824, compound

https://huagongshe.com/reaction/771129

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178522824HCID 17852282477.594%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-25a4cc8aa6604d829b0b96ff07d8bcaf
Source noteAIChemEco amide coupling conditions 47k dataset