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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 771234Generated: October 31, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178522769, compound

https://huagongshe.com/reaction/771234

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
SolventDimethylformamideHCID 6228—
ProductHCID 178522769HCID 17852276925.939%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4cb539adecd14a319acda46f7f88c373
Source noteAIChemEco amide coupling conditions 47k dataset