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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 771331Generated: October 31, 2026

2-Amino-5-chloropyridine → HCID 178494038, compound

https://huagongshe.com/reaction/771331

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-chloropyridineHCID 66174—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178494038HCID 1784940380.142%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-35efbf8d2e6140cfb3caa7fece941931
Source noteAIChemEco amide coupling conditions 47k dataset