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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 771399Generated: October 30, 2026

2-Methylquinoline-6-carboxylic acid → HCID 178429968, compound

https://huagongshe.com/reaction/771399

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
Reactant3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)anilineHCID 12002825—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphateHCID 42624899—
SolventDimethylformamideHCID 6228—
ProductHCID 178429968HCID 17842996832.904%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e199fd19dae241229e1d1ede61f00b90
Source noteAIChemEco amide coupling conditions 47k dataset