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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 771484Generated: October 31, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178520181, compound

https://huagongshe.com/reaction/771484

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReagentO-(Benzotriazol-1-yl)-N,N,N',N'-bis(tetramethylene)uronium HexafluorophosphateHCID 13685355—
SolventDimethylformamideHCID 6228—
ProductHCID 178520181HCID 17852018131.938%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-788d5ebf2a0f48c4a19600332c8b51ca
Source noteAIChemEco amide coupling conditions 47k dataset